Comment in 2021

In this comment, Professor Christian Beste discusses the disconnection between psychology and neuroscience and the effects this can have on the progress of both fields and reproducibility. He also considers the role that publishers can play in strengthening the connections between the disciplines.

Cunningham et al. comment on the U.K.’s commitment to protect 30% of land by 2030, by identifying priority landscapes for expansion of the current protected area network in the UK using 445 priority species ranges across the country, under two baseline protection definitions to reach this conservation target. They find that expanding the protected area network by initially only including the strictest protected areas would yield much greater representation of threatened species, and propose new considerations for protected area commitments.

Jasmine Miller-Kleinhenz et al. highlight the risk of science and academia’s general neutrality to discussions around race and social justice. Their collectively-developed course represents a framework to begin these important discussions and improve conversations on race in academia.

García Saura et al. report a new tool, MacroGreen, to detect ADP-ribosylation by GFP fluorescence in a microplate reader, or in cells by microscopy. With superior affinity and reduced ADP-ribosyl hydrolase activity, MacroGreen is an easy to produce and suitable tool for rapid detection of ADP-ribosylated proteins in vitro without a need for specialist reagents and time-consuming methods.

In a recent issue of Science Advances, Srivastava et al. report a novel nucleotide biosynthesis regulatory role for UBR7 in NOTCH1-driven T-ALL. Here we will discuss their key findings and the implications for using cancer metabolism to understand the development and progression of T-ALL.