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VersaLive is a versatile microfluidic platform with flexible input modes and low-volume media reservoirs that can be used for time-lapse live cell imaging, immunostaining, cell recovery, cell lysis and plasmid transfection.
Myanmar amber collection and study in palaeontology is clouded with ethical and legal issues. Here, the history and legality of Myanmar amber use in the literature is reviewed.
European megafaunal ungulates living in open habitats over the last 50,000 years showed evidence for niche change, possibly driven by climatic change and extinction of competitors and predators
Proteomic analysis of human early fetal brain tissue is undertaken to investigate bilateral developmental changes of protein expression and left-right asymmetries of protein expression.
A CTCF mediated intrachromosomal looping of RB1 promoter and its downstream silencer served as a regulatory inducer to inactivate RB1, revealing a novel transcriptional mechanism underlying RB1 dysfunction independent of gene mutation.
Thymic architecture and T cell repertoire analysis of a mouse model for thymoma and the role of the transcription factor GTF2I shows suitability of this model to recapitulate human thymomas and a severe effect of Gtf2i mutations on the medullary compartment.
A clinical influenza isolate with dual antiviral resistant mutations displays a moderate loss of viral fitness in ferrets compared to wild-type virus, suggesting widespread community transmission of this dual mutant is unlikely.
Dimension reduction methods on porcine sperm motility landscapes reveal heterogeneity and hierarchy in sperm movement behavior and show high-speed and straight-lined motion as predictive features of fertility.
The Grb2 splice variant Grb3-3 results in decreased activation of the Ras-MAPK pathway due competition with Grb2 for SOS binding, with reduced Grb3-3 levels observed in tumour tissue suggestive of a mechanism for enhancing Ras pathway activity.
Chimpanzees are known to suffer from malaria parasitism. Here, the prevalence and epidemiology of several malaria parasites is examined in a wild chimpanzee population.
A giant vesicle system combines fatty acid synthesis pathways, CoA recycling, and cell-free acyltransferase gene expression to perform phospholipid synthesis inside.
Individuals across six major psychiatric conditions from the ENIGMA consortium reveals a shared morphological effect, following a sensory-fugal axis, which is related to microstructural gradient and neurotransmitter axes.
Low temperature inhibits the regeneration of amputated tails of Gekko japonicus by influencing the energy sensory Akt/mTOR pathway, which is also modulated by injury-induced Wnt signal.
A review of the function of the Dystrophic Glycoprotein Complex (DGC) in mechanosignaling provides an overview of the various components of DGC and potential mechanopathogenic mechanisms, particularly as they relate to muscular dystrophy.
Kinetics of cargo degradation in phagosomes are measured through engineered RotSensors, capturing their translational and rotational dynamics in parallel.