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Frontiers in Biology

Vol. 481 No. 7381 pp277-320

In this Supplement
- Editorial
- Articles
The regular Insight 'Frontiers in Biology' covers important developments in biology. Reviews include innate immune signalling in tissue homeostasis, the DNA damage response in cancer treatment, therapeutic promise of patient-derived pluripotent stem cells, clonal evolution in cancer and the impact of mouse genetics on the study of bone physiology.

Credit: Nik Spencer

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Inflammasomes in health and disease
- Till Strowig
- Jorge Henao-Mejia
- Eran Elinav
- Richard Flavell
Nature 481, 278-286 (19 January 2012)
The DNA damage response and cancer therapy
- Christopher J. Lord
- Alan Ashworth
Nature 481, 287-294 (19 January 2012)
The promise of induced pluripotent stem cells in research and therapy
- Daisy A. Robinton
- George Q. Daley
Nature 481, 295-305 (19 January 2012)
Clonal evolution in cancer
- Mel Greaves
- Carlo C. Maley
Nature 481, 306-313 (19 January 2012)
The contribution of bone to whole-organism physiology
- Gérard Karsenty
- Mathieu Ferron
Nature 481, 314-320 (19 January 2012)

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