WEB FOCUS
HapMap
In this focus:
Current research | Weblinks | Archive
The goal of the International HapMap Project is to develop a haplotype map of the human genome, the HapMap, which aims to describe the common patterns of human DNA sequence variation.
The International HapMap Project has mapped the haplotypes of several human populations based on over a million single changes. The HapMap is expected to be a key freelay available resource for researchers to find genes affecting health, disease, and responses to drugs and environmental factors.
In this Web Focus we present the first edition of the International HapMap project. See Nature's Human Genome Collection for the definitive historical record of the sequences and analyses of the Human Genome Project. Image: Fuli Yu
Current research
ARTICLE
A haplotype map of the human genome Free access
The International HAPMAP consortium
Nature 437, 1299-1320 (27 Oct 2005) doi:10.1038/nature04226
LETTER
Mapping determinants of human gene expression by regional and genome-wide association Free access
Vivian G. Cheung et al
Nature 437, 1365-1369 (27 Oct 2005) doi:10.1038/nature04244
NEWS AND VIEWS
Genomics: Understanding human diversity Free access
David B. Goldstein and Gianpiero L. Cavalleri
Nature, 437, 1241 (27 Oct 2005) doi:10.1038/4371241a
COMMENTARY
Deeper into the genome
Richard Gibbs
Nature, 437, 1233-1234 (27 Oct 2005) doi:10.1038/4371233a
Top of pageWeb links
- Human Genome Collection
- The International HapMap project
- Genome Research Special issue
- Genome Gateway
- The chimpanzee genome Web Focus
- The Y chromosome Web Focus
- 50 years of DNA Web Focus
- News@nature.com X Chromosome — In Focus
- News@nature.com Special — Chimpanzee genome
- Nature Insight: Human genomics and medicine
Archive
NEWS AND VIEWS
Human genome: End of the beginning Free access
Just over three years ago, it was announced that a first draft of the human genome sequence had been completed. In this News and Views article, Lincoln Stein describes how gaps and errors remained, but the job of fixing those problems is now largely done.
Nature 431, 915 - 916 (1 October 2004)
ARTICLE
Finishing the euchromatic sequence of the human genome Free access
International Human Genome Sequencing Consortium
Nature 431, 931 - 945 (21 October 2004)
ANALYSIS
Quality assessment of the human genome sequence Free access
Schmutz J. et al
Nature 429, 365-368 (27 May 2004)
NEWS FEATURE
The rough guide to the genome Free access
A new effort to map human genetic variation should provide a shortcut for researchers trying to uncover the roots of disease. Carina Dennis profiles the 'HapMap' project.
Nature 425, 758 - 759 (23 October 2003)
FEATURE
A vision for the future of genomics research Free access
Francis S. Collins, Eric D. Green, Alan E. Guttmacher & Mark S. Guyer
Nature 422, 835 - 847 (2003)
ARTICLE
Initial sequencing and analysis of the human genome Free access
The Genome International Sequencing Consortium
Nature 409 860-921 (15 February 2001)