WEB FOCUS

HapMap

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Current research | Weblinks | Archive

The goal of the International HapMap Project is to develop a haplotype map of the human genome, the HapMap, which aims to describe the common patterns of human DNA sequence variation.

The International HapMap Project has mapped the haplotypes of several human populations based on over a million single changes. The HapMap is expected to be a key freelay available resource for researchers to find genes affecting health, disease, and responses to drugs and environmental factors.

In this Web Focus we present the first edition of the International HapMap project. See Nature's Human Genome Collection for the definitive historical record of the sequences and analyses of the Human Genome Project. Image: Fuli Yu

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Current research

ARTICLE

A haplotype map of the human genome Free access

The International HAPMAP consortium

Nature 437, 1299-1320 (27 Oct 2005) doi:10.1038/nature04226

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LETTER

Mapping determinants of human gene expression by regional and genome-wide association Free access

Vivian G. Cheung et al

Nature 437, 1365-1369 (27 Oct 2005) doi:10.1038/nature04244

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NEWS AND VIEWS

Genomics: Understanding human diversity Free access

David B. Goldstein and Gianpiero L. Cavalleri

Nature, 437, 1241 (27 Oct 2005) doi:10.1038/4371241a

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COMMENTARY

Deeper into the genome

Richard Gibbs

Nature, 437, 1233-1234 (27 Oct 2005) doi:10.1038/4371233a

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Web links

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Archive

NEWS AND VIEWS

Human genome: End of the beginning Free access

Just over three years ago, it was announced that a first draft of the human genome sequence had been completed. In this News and Views article, Lincoln Stein describes how gaps and errors remained, but the job of fixing those problems is now largely done.

Nature 431, 915 - 916 (1 October 2004)

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ARTICLE

Finishing the euchromatic sequence of the human genome Free access

International Human Genome Sequencing Consortium

Nature 431, 931 - 945 (21 October 2004)

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ANALYSIS

Quality assessment of the human genome sequence Free access

Schmutz J. et al

Nature 429, 365-368 (27 May 2004)

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NEWS FEATURE

The rough guide to the genome Free access

A new effort to map human genetic variation should provide a shortcut for researchers trying to uncover the roots of disease. Carina Dennis profiles the 'HapMap' project.

Nature 425, 758 - 759 (23 October 2003)

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FEATURE

A vision for the future of genomics research Free access

Francis S. Collins, Eric D. Green, Alan E. Guttmacher & Mark S. Guyer

Nature 422, 835 - 847 (2003)

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ARTICLE

Initial sequencing and analysis of the human genome Free access

The Genome International Sequencing Consortium

Nature 409 860-921 (15 February 2001)

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