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Regulatory RNA

Vol. 482 No. 7385 pp321-355

In this Supplement
- Editorial
- Articles
In-depth sequencing studies have revealed an unexpected complexity to the nature and function of RNAs encoded by DNA. This Insight includes an explanation of how dynamic reorganization of RNA structure directs many cellular processes, discusses systems controlled by specific RNAs and offers a modular model for the function of long non-coding RNAs.

Credit: Nik Spencer

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Functional Complexity And Regulation Through RNA Dynamics
- Elizabeth A. Dethoff
- Jeetender Chugh
- Anthony M. Mustoe
- Hashim M. Al-Hashimi
Nature 482, 322-330 (16 February 2012)
RNA-guided genetic silencing systems in bacteria and archaea
- Blake Wiedenheft
- Samuel H. Sternberg
- Jennifer A. Doudna
Nature 482, 331-338 (16 February 2012)
Modular regulatory principles of large non-coding RNAs
- Mitchell Guttman
- John L. Rinn
Nature 482, 339-346 (16 February 2012)
The microcosmos of cancer
- Amaia Lujambio
- Scott W. Lowe
Nature 482, 347-355 (16 February 2012)