Collection 

Innovations in cancers of the central nervous system

Submission status
Closed
Submission deadline

This Collection aims to highlights the latest advances in research in brain cancers, with a focus on adult diffuse gliomas, glioblastomas, meningiomas and metastatic brain tumors. Tumors affecting the brain cause substantial morbidity and mortality and there is a significant need for improved detection, non-invasive monitoring strategies and more effective and durable treatments. The focus of the collection will be on recent advances in basic, translational and clinical research as well as offer expert commentary on strategies to move brain cancer diagnostics and therapeutics forward.

Topics of interest include:

  • Advances in liquid biopsy for diagnosis and monitoring of nervous system cancers
  • Preclinical disease models (patient-derived xenografts, organoids, genetically engineered models)
  • Innovations in Immunotherapy
  • Metabolic dysregulation in glioma
  • Targeted therapies and resistance in brain tumors
  • Cancer neuroscience and tumor-microenvironment
  • Advances in imaging techniques
  • Strategies for increasing CNS permeability of therapeutic agents
  • Applications of Artificial Intelligence/Machine Learning to brain cancers

This Collection supports and amplifies research related to SDG 3.

Graphical representation of a brain with a bright spot in the center signifying the presence of cancer cells

Editors

  • Julie J. Miller

    Massachusetts General Hospital, Harvard Medical School, USA.

  • Albert Kim

    Massachusetts General Hospital, Harvard Medical School, USA.