Nature Reviews Urology is proud to present the Men's Health Collection in partnership with the Movember Foundation.

The issue of men's health has increased in the public awareness in recent years and emerged as a new discipline that is responsible for a gender-specific approach to health-services delivery, government policy, research, and advocacy. An improved focus on men's health is needed as the average life expectancy for men is lower than for women in almost all countries and social influences mean that, often, men do not see their health as a priority. Charities have had a major role in promoting men's health as an issue for society in general, as well as providing support and funding for research.

This special collection of articles by key opinion leaders highlights issues that are important to men, their families, and their physicians, and provides a resource for these interested parties in the areas of prostate cancer, BPH, fertility, and testosterone deficiency. The male-health paradigm and the influence of charities in championing this important cause are also discussed.

All content has been chosen by the editors of Nature Reviews Urology.


Health policy: Male health—a recent paradigm

S. Larry Goldenberg & Alan White


Nature Reviews Urology 12, 15-16 (2015)

The influence of charities in the field of men's health

Dan Wood & Suks Minhas


Nature Reviews Urology, advance online publication, Published online 28th October 2015


New intraprostatic injectables and prostatic urethral lift for male LUTS

Giuseppe Magistro, Christian G. Stief & Christian Gratzke


Nature Reviews Urology 12, 461-471 (2015)

Interest is growing in minimally invasive treatment options male lower urinary tract symptoms (LUTS), and preservation of all aspects of sexual function is increasingly important for patients. Here, the authors discuss initial experimental data on new minimally invasive procedures, such as the intraprostatic injection of novel agents, and the mechanical prostatic urethral lift device—Urolift® (Neotract, Inc., USA) for the treatment of LUTS caused by BPH.

Effects of psychological stress on male fertility

Vinod H. Nargund


Nature Reviews Urology 12, 373-382 (2015)

Many clinical studies looking at the effects of psychological stress on male fertility have shown that stress is associated with reduced paternity and abnormal semen parameters. This Review by Nargund describes the possible effects of psychological stress on testosterone secretion and spermatogenesis.

Switching and withdrawing hormonal agents for castration-resistant prostate cancer

David Lorente, Joaquin Mateo, Zafeiris Zafeiriou, Alan D. Smith, Shahneen Sandhu, Roberta Ferraldeschi & Johann S. de Bono


Nature Reviews Urology 12, 37-47 (2015)

The antiandrogen withdrawal syndrome (AAWS) is characterized by tumour regression on treatment discontinuation. Here, the mechanisms of AAWS and the development of treatment resistance are described, and the implications for the development of novel drugs and the challenges associated with redefining the utility of older treatments are discussed.


Psychosocial perspectives on sexual recovery after prostate cancer treatment

Lauren M. Walker,Richard J. Wassersug & John W. Robinson


Nature Reviews Urology 12, 167-176 (2015)

Many patients experience impaired erectile function after prostate cancer treatment and struggle to resume a satisfying sexual relationship. In this Perspectives article, Walker, Robinson and Wassersug provide healthcare professionals with recommendations to facilitate successful sexual recovery and the best outcome for patients and their partners.

The practical management of testosterone deficiency in men

Antonio Aversa & Abraham Morgentaler


Nature Reviews Urology, advance online publication, Published online 13th October 2015

Global interest in testosterone deficiency in men and its treatment with testosterone therapy has increased, but practical aspects of care remain confusing to many practitioners. Here, Aversa and Morgentaler describe the symptoms, signs, and diagnosis of testosterone deficiency and discuss the options for testosterone therapy and treatment monitoring, along with its clinical benefits.


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