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Since late 2019, a novel virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a new public health crisis. Although scientists have primarily focused on keeping patients alive by preventing the deadly symptoms of the coronavirus disease 2019 (COVID-19), studies have shown that the virus can also impair quality of life by deteriorating sexual and reproductive systems. In this collection, we aim to provide insights related to the novel coronavirus's neglected effects on human sexuality. We hope that scientists will focus more on "COVID-19 and Sexuality" in the future and identify optimal management strategies for individuals who suffer from sexual side effects of coronavirus.