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Montoya-Salazar V, Castillo-Oyagüe R et al. J Dent 2014; 42: 645–652

All patients in this study 1) were prescribed azithromycin 250 mg/day for 5 days one month before surgery, 2) 1.5 g of amoxicillin, 4 days before implant placement, and 3) 1.5 g of amoxicillin for 6 days after surgery. Infected sockets only, were 1) curetted and debrided, 2) irrigated with 90% hydrogen peroxide, 3) laser irradiated, and 4) finally irrigated with saline. This was a prospective study over 36 months and the investigators recruited 18 patients. It was a split-mouth design; on one side of the mouth the implant was placed in the infected and treated socket, and on the other side a non-infected socket. The implant site preparation was extended apically 3–4 mm, and 13 mm length implants were stabilised with bovine bone. Second-stage surgery was carried out after 3 months. After 3 years, there were no differences in clinical and radiographic measurements. The 3-year survival rate was 94.44% for those implants placed in the infected and treated sockets and 100% in the uninfected sockets.