A recent study by the GIGASTROKE consortium combines genetic discovery, fine-mapping and proteomic data to identify causal genes and variants related to disease. Results reveal known and new targets for prevention or treatment of stroke, and highlight the importance of genomics for drug discovery and development.
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Acknowledgements
D.K. is supported by the Department of Veterans Affairs Office of Research Development, IK2 BX 005759-01.
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D.K. is a scientific advisor and reports consulting fees from Bitterroot Bio, unrelated to the present work.
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Klarin, D. Prioritizing treatments for stroke through human genetics. Nat Cardiovasc Res 1, 876–877 (2022). https://doi.org/10.1038/s44161-022-00132-7
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DOI: https://doi.org/10.1038/s44161-022-00132-7