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Atomic-scale manufacturing

Single-molecule chemistry with a smart robot

Artificial intelligence is used to automate the synthesis of single molecules using the tip of a scanning probe microscope, as well as to extract chemical information from these reactions.

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Fig. 1: Autonomous SPM operation to synthesize a magnetic nanographene.

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The authors declare no competing interests.

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Correspondence to J. Michael Gottfried.

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Ruan, Z., Gottfried, J.M. Single-molecule chemistry with a smart robot. Nat. Synth 3, 424–425 (2024). https://doi.org/10.1038/s44160-024-00504-w

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