Biomimetic nanoparticles can form complexes with proteins. Structural descriptors have been identified to predict nanoparticle–protein complex formation and their interaction sites. These descriptors include geometrical and graph-theoretical molecular features that are universally applicable to all nanoscale macromolecules of both organic and inorganic chemistries.
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References
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This is a summary of: Cha, M. et al. Unifying structural descriptors for biological and bioinspired nanoscale complexes. Nat. Comput. Sci. https://doi.org/10.1038/s43588-022-00229-w (2022).
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Universal descriptors to predict interactions of inorganic nanoparticles with proteins. Nat Comput Sci 2, 294–295 (2022). https://doi.org/10.1038/s43588-022-00230-3
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DOI: https://doi.org/10.1038/s43588-022-00230-3