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Completing the cancer jigsaw puzzle with single-cell multiomics

Recent advances in single-cell multiomics have provided holistic views of the multifaceted state of a cell and its interaction with the environment. The rapid development of these technologies has offered a unique opportunity to analyse the molecular and cellular heterogeneity in cancer, and could lead to better cancer diagnosis, treatment and prognosis.

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Fig. 1: Timeline of single-cell multiomics sequencing technologies.

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Correspondence to Song Chen or Sarah A. Teichmann.

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Over the last three years, S.A.T. has received remuneration for consulting or scientific advisory board membership at Genentech, Roche, Biogen, GlaxoSmithKline, Qiagen, Foresite Labs and Transition Bio, and is an equity holder of Transition Bio.

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Chen, S., Teichmann, S.A. Completing the cancer jigsaw puzzle with single-cell multiomics. Nat Cancer 2, 1260–1262 (2021). https://doi.org/10.1038/s43018-021-00306-5

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