Cryo-EM analysis reveals the mechanism by which chromatin is compacted at the centromere by the H3 histone variant CENP-N. Intriguingly, despite the structural differences between CENP-N and linker H1 histones, both appear to similarly compact higher-order nucleosome structures.
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Good, K.V., Ausió, J. Chromatin, stacked at the centromere. Nat Struct Mol Biol 29, 288–290 (2022). https://doi.org/10.1038/s41594-022-00759-x
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DOI: https://doi.org/10.1038/s41594-022-00759-x
