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Inefficient splicing curbs noncoding RNA transcription

An Author Correction to this article was published on 01 April 2021

This article has been updated

Pervasive genome-wide transcription initiation by RNA polymerase II (Pol II) necessitates mechanisms that restrain the quantity and length of the transcripts. A new study investigates a mechanism for inducing early transcription termination, employed primarily at genomic regions producing noncoding RNAs.

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Fig. 1: The WDR82–ZC3H4 complex curbs noncoding RNA transcription.

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Correspondence to Noa Gil or Igor Ulitsky.

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Gil, N., Ulitsky, I. Inefficient splicing curbs noncoding RNA transcription. Nat Struct Mol Biol (2021).

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