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BACTERIAL ENVELOPE

Aboard the LetB express

How Gram-negative bacteria transport glycerophospholipids between membranes remains a major point of inquiry for cell envelope biologists. Two groups report cryo-EM structures and functional studies of LetB (YebT), providing support for its involvement in cell envelope maintenance.

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Fig. 1: LetB architecture and substrate transport.
Fig. 2: Potential models for the interaction of LetB with the outer membrane (OM).

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Correspondence to M. Stephen Trent.

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Powers, M.J., Trent, M.S. Aboard the LetB express. Nat Struct Mol Biol 27, 403–405 (2020). https://doi.org/10.1038/s41594-020-0431-7

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