MEMBRANE CHANNELS

Structures of CALHM channels revealed

Recent studies report the first structures of two CALHM family members, describing unexpected oligomeric architecture and providing insights into the mechanism of function of CALHM channels.

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Fig. 1: Structures of CALHM1 and CALHM2.
Fig. 2: Displacment of TM1 by RuR in CALHM2.

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Correspondence to J. Kevin Foskett.

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Foskett, J.K. Structures of CALHM channels revealed. Nat Struct Mol Biol 27, 227–228 (2020). https://doi.org/10.1038/s41594-020-0391-y

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