Researchers repurpose cytosine deaminase toxin DddA to measure DNA–protein interaction sites in bacteria.
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Research paper
Gallagher, L. A. et al. Genome-wide protein–DNA interaction site mapping in bacteria using a double-stranded DNA-specific cytosine deaminase. Nat. Microbiol. 7, 844–855 (2022).
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Tang, L. Recording protein–DNA interactions in bacteria. Nat Methods 19, 782 (2022). https://doi.org/10.1038/s41592-022-01556-6
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DOI: https://doi.org/10.1038/s41592-022-01556-6