Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

Integrating experiments, theory and simulations into whole-cell models

Nature Methods volume 18, pages 446–447 (2021)Cite this article

Subjects

Whole-cell models, still in the early stages of development, are poised to open the next frontier in integrative modeling.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Workflow for whole-cell simulations.

References

  1. Hutchison, C. A. III et al. Science 351, aad6253 (2016).

    Article  Google Scholar 

  2. Breuer, M. et al. eLife 2019, e36842 (2019).

    Article  Google Scholar 

  3. Thornburg, Z. R. et al. Front. Mol. Biosci. 6, 130 (2019).

    Article  CAS  Google Scholar 

  4. Hallock, M. J., Stone, J. E., Roberts, E., Fry, C. & Luthey-Schulten, Z. Parallel Comput. 40, 86–99 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA

    Zaida Luthey-Schulten

Authors
  1. Zaida Luthey-Schulten
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Zaida Luthey-Schulten.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Luthey-Schulten, Z. Integrating experiments, theory and simulations into whole-cell models. Nat Methods 18, 446–447 (2021). https://doi.org/10.1038/s41592-021-01150-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41592-021-01150-2

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing