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3D GENOMICS

Benchmarking experiments with polymer modeling

A study applies polymer physics to assess the advantages and limitations of three sequencing-based approaches for determining the structure of genomes and genomic domains.

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Fig. 1: Computational modeling bypasses the difficulties for benchmarking and assessing the performances of Hi-C, SPRITE and GAM for determining the structure of genomes and genomic domains.

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Correspondence to Marc A. Marti-Renom.

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Marti-Renom, M.A. Benchmarking experiments with polymer modeling. Nat Methods 18, 456–457 (2021). https://doi.org/10.1038/s41592-021-01134-2

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