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Metabolic diseases

New insights into the genetics of diabetes in pregnancy

Gestational diabetes is a complex metabolic condition thought to have a strong genetic predisposition. A large genome-wide association study of participants from Finland sheds light on the genetic contributors, opening avenues for research into mechanisms that underlie glucose regulation in pregnancy to improve the health of mothers and babies.

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Fig. 1: Prior associations of 14 genome-wide significant loci for GDM with T2D and fasting glucose levels.

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Correspondence to Rachel M. Freathy.

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Cissé, A.H., Freathy, R.M. New insights into the genetics of diabetes in pregnancy. Nat Genet 56, 358–359 (2024). https://doi.org/10.1038/s41588-024-01675-0

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