MATERNAL OBESITY

Eggs sense high-fat diet

Maternal high-fat diet has a negative impact on fertility—including an apparent direct effect on early development. In this issue, a new study connects this phenotype to depletion of Stella protein in oocytes, demonstrating environmental regulation of a maternal-effect gene.

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Fig. 1: Reduction of maternally inherited Stella protein in occytes provides a possible molecular link between high-fat diet and reduced fertility in females.

Marina Corral Spence/Springer Nature.

Change history

  • 21 June 2018

    In the version of this article originally published, a box was misplaced in Fig. 1. The error has been corrected in the HTML and PDF versions of the article.

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Correspondence to Petra Hajkova.

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Leitch, H.G., Hajkova, P. Eggs sense high-fat diet. Nat Genet 50, 318–319 (2018). https://doi.org/10.1038/s41588-018-0068-1

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