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New IDEAS about amyloid, race and dementia disparities

In a study of 17,000 Medicare beneficiaries with mild cognitive impairment or dementia, non-Hispanic white older adults were more likely than Asian, Black or Hispanic older adults to have elevated cortical amyloid, as measured by PET. These findings have important implications for the use of amyloid-targeting therapies.

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Fig. 1: The estimated relative contributions of sociodemographic, clinical and biological factors to cognitive impairment across racial and ethnic groups.


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The authors are supported by the Intramural Research Program of the NIH, National Institute on Aging.

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Correspondence to Keenan A. Walker.

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The authors declare no competing interests.

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Dark, H.E., Walker, K.A. New IDEAS about amyloid, race and dementia disparities. Nat Rev Neurol 19, 5–6 (2023).

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