Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

STROKE

Is post-stroke cognitive impairment all about real estate?

Nature Reviews Neurology volume 17, pages 465–466 (2021)Cite this article

Subjects

An international consortium analysis has shown that stroke location strongly predicts post-stroke cognitive impairment, but the effect could be confounded by the characteristics of the infarct and of different patients. Taking pre-stroke cognition and risk factors into consideration might put information about infarct location into a more appropriate context.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Weaver, N. A. et al. Strategic infarct locations for post-stroke cognitive impairment: a pooled analysis of individual patient data from 12 acute ischaemic stroke cohorts. Lancet Neurol. 20, 448–459 (2021).

    Article  Google Scholar 

  2. Censori, B. et al. Dementia after first stroke. Stroke 27, 1205–1210 (1996).

    Article  CAS  Google Scholar 

  3. Schellhorn, T. et al. Clinically accessible neuroimaging predictors of post-stroke neurocognitive disorder: a prospective observational study. BMC Neurology 21, 89 (2021).

    Article  Google Scholar 

  4. Johansen, M. C. & Gottesman, R. F. Cerebrovascular disease and cognitive outcome in patients with cardiac disease. Semin. Neurol. https://doi.org/10.1055/s-0041-1726330 (2021).

    Article  PubMed  Google Scholar 

  5. Chen, L. Y. et al. Association of atrial fibrillation with cognitive decline and dementia over 20 years: The ARIC NCS (Atherosclerosis Risk in Communities Neurocognitive Study). J. Am. Heart Assoc. 7, e007301 (2018).

    PubMed  PubMed Central  Google Scholar 

  6. Lo, J. W. et al. Profile or and risk factors for poststroke cognitive impairment in diverse ethnoregional groups. Neurology 93, e2257–e2271 (2019).

    Article  Google Scholar 

  7. Molad, J. et al. Vascular and neurodegenerative markers for the prediction of post-stroke cognitive impairment: Results from the TABASCO study. J. Alzheimers Dis. 70, 889–898 (2019).

    Article  CAS  Google Scholar 

  8. Pendlebury, S. T. & Rothwell, P. M. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol. 8, 1006–1018 (2009).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Stroke Branch, National Institute of Neurological Disorders and Stroke Intramural Research Program, National Institutes of Health, Bethesda, MD, USA

    Rebecca F. Gottesman

Authors
  1. Rebecca F. Gottesman
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rebecca F. Gottesman.

Ethics declarations

Competing interests

The author declares no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gottesman, R.F. Is post-stroke cognitive impairment all about real estate?. Nat Rev Neurol 17, 465–466 (2021). https://doi.org/10.1038/s41582-021-00526-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41582-021-00526-4

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing