A new meta-analysis of placebo-controlled trials of calcitonin gene-related peptide (CGRP) antibodies for migraine has shown that the direct biological effects of these treatments beyond the effects of placebo are modest, raising questions about how the ‘true value’ of these and other drugs are assessed.
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Applying a biopsychosocial model to migraine: rationale and clinical implications
The Journal of Headache and Pain Open Access 11 August 2022
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Loder, E.W., McGeeney, B. Disentangling placebo effects in the treatment of migraine. Nat Rev Neurol 16, 657–658 (2020). https://doi.org/10.1038/s41582-020-0406-7
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DOI: https://doi.org/10.1038/s41582-020-0406-7
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Applying a biopsychosocial model to migraine: rationale and clinical implications
The Journal of Headache and Pain (2022)