A new study has identified an association between socioeconomic status and the risk of disability in individuals with multiple sclerosis. The findings highlight the importance of collecting large, structured datasets for the study of modifiable risk factors.
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References
Ramanujam, R. et al. Effect of smoking cessation on multiple sclerosis prognosis. JAMA Neurol. 72, 1117–1123 (2015).
Trojano, M. et al. Treatment decisions in multiple sclerosis - insights from real-world observational studies. Nat. Rev. Neurol. 13, 105–118 (2017).
Calocer, F. et al. Socioeconomic deprivation increases the risk of disability in Multiple Sclerosis patients. Mult. Scler. Relat. Disord. 40, 101930 (2020).
Vukusic, S. et al. Observatoire Français de la Sclérose en Plaques (OFSEP): A unique multimodal nationwide MS registry in France. Mult. Scler. 26, 118–122 (2020).
Harding, K. E. et al. Socioeconomic status and disability progression in multiple sclerosis: A multinational study. Neurology 92, e1497–e1506 (2019).
Kingwell, E. et al. Causes that contribute to the excess mortality risk in multiple sclerosis: a population-based study. Neuroepidemiology https://doi.org/10.1159/000504804 (2019).
Leray, E. et al. Excess mortality in patients with multiple sclerosis starts at 20 years from clinical onset: data from a large-scale french observational study. PLoS One. 10, e0132033 (2015).
Manouchehrinia, A. et al. Association of pre-disease body mass index with multiple sclerosis prognosis. Front. Neurol. 9, 232 (2018).
McKay, K. A. et al. Psychiatric comorbidity is associated with disability progression in multiple sclerosis. Neurology 90, e1316–e1323 (2018).
Binzer, S., McKay, K. A., Brenner, P., Hillert, J. & Manouchehrinia, A. Disability worsening among persons with multiple sclerosis and depression: A Swedish cohort study. Neurology 93, e2216–e2223 (2019).
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J.H. has received honoraria for serving on advisory boards for Biogen, Celgene, Merck KGaA, Novartis, Sandoz and Sanofi Genzyme and speaker’s fees from Biogen, Merck KGaA, Novartis, Sanofi Genzyme and Teva. He has served as principal investigator for projects, or received unrestricted research support from, Biogen, Celgene, Merck KGaA, Novartis, Roche and Sanofi Genzyme. His multiple sclerosis research is funded by the Swedish Research Council and the Swedish Brain foundation.
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Hillert, J. Socioeconomic status and multiple sclerosis outcome. Nat Rev Neurol 16, 191–192 (2020). https://doi.org/10.1038/s41582-020-0329-3
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DOI: https://doi.org/10.1038/s41582-020-0329-3
