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Stroke prediction and the future of prognosis research

In a new study of 1,102 patients, a multi-item prognostic tool has been developed and validated for use in acute stroke. Using a mix of clinical variables (age and stroke severity), a process variable (administration of thrombolysis) and a biomarker (plasma copeptin), the authors were able to predict 3-month disability.

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Acknowledgements

T.J.Q. is supported by a joint Chief Scientist Office and Stroke Association Senior Lectureship, grant reference TSA LECT 2015/05. B.A.D. is supported through the Stroke Association Priority Program Award, grant reference PPA 2015/01_CSO.

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Competing interests

The authors declare no competing interests.

Correspondence to Terence J. Quinn.

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DOI

https://doi.org/10.1038/s41582-019-0181-5

Fig. 1: Outcome predictions based on the CoRisk score in a hypothetical sample of stroke patients.