A new study has identified novel genes involved in sporadic frontotemporal lobar degeneration with neuronal inclusions of TAR DNA-binding protein 43. These findings might enable the elucidation of pathogenic mechanisms of the disease and have implications for the identification of potential therapeutic targets.
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Galimberti, D. Genetic risk factors and role of immune dysfunction in FTLD. Nat Rev Neurol 15, 250–251 (2019). https://doi.org/10.1038/s41582-019-0173-5
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DOI: https://doi.org/10.1038/s41582-019-0173-5
