Intensive lowering of blood pressure can decrease the risk of death and cardiovascular events in individuals with hypertension. However, a reanalysis of data from the SPRINT and ACCORD trials suggests that intensive blood pressure lowering increases the risk of chronic kidney disease.
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Acknowledgements
The authors are supported by the US National Institutes of Health (grants DK116196 and DK096373 to M.L.S.S.-L. and DK116718 and DK096373 to R.A.G.).
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Sequeira-Lopez, M.L.S., Gomez, R.A. Preserving kidney health during intensive blood pressure control. Nat Rev Nephrol 14, 537–538 (2018). https://doi.org/10.1038/s41581-018-0034-2
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DOI: https://doi.org/10.1038/s41581-018-0034-2
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