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  • Review Article
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Materials, assemblies and reaction systems under rotation

Nature Reviews Materials volume 7, pages 338–354 (2022)Cite this article

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Abstract

When liquids or solid materials rotate, they impart centrifugal and/or shear forces. This Review surveys rotary devices and systems in which such forces control small-scale flows, self-organization phenomena, materials synthesis or chemical reactivity at molecular and macromolecular levels. Centrifugal forces directed away from the rotation axis enable various separations or lab-on-a-disc systems and can shape interfaces or deposit thin films of functional materials. When these forces act on particles lighter than the rotating fluid, they can provide the basis for colloidal crystallization or trapping; when the direction of rotation changes, they can simulate microgravity conditions and affect motility patterns of living organisms. Shear forces, by contrast, can promote crystallization, couple to molecular-scale assembly and affect its chiral outcomes. Combining centrifugal and shear forces is useful in establishing rotating reactors to accelerate reaction kinetics, modulate chemical reactivity, enable multistep syntheses or support complex extractions. Through these and other examples, we illustrate that rotating reaction vessels can enable new types of chemical experimentation, with outcomes that are not always understood. We argue that rotating systems for studying such processes will become more common given advances in remotely controlled sensors and spectrometers that can monitor the contents of rotating vessels.

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Fig. 1: Forces in rotating frames of reference.
Fig. 2: Unconventional centrifuges and lab-on-a-disc systems.
Fig. 3: Self-assembly and trapping in rotating liquids.
Fig. 4: Free liquid surfaces and thin films under rotation.
Fig. 5: Shear-enhanced growth of crystals in the presence of polymers.
Fig. 6: Concentric liquid layers and their use as chemical reactors.

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Acknowledgements

This work was supported by the Institute for Basic Science, Republic of Korea (IBS-R020-D1) and by the National Science Center, Poland (grant Maestro, no. 2018/30/A/ST5/00529).

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Authors and Affiliations

  1. IBS Center for Soft and Living Matter, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea

    Bartosz A. Grzybowski, Yaroslav I. Sobolev & Olgierd Cybulski

  2. Department of Chemistry, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea

    Bartosz A. Grzybowski

  3. Institute of Organic Chemistry, Polish Academy of Sciences, Warsaw, Poland

    Bartosz A. Grzybowski & Barbara Mikulak-Klucznik

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  1. Bartosz A. Grzybowski
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  2. Yaroslav I. Sobolev
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  4. Barbara Mikulak-Klucznik
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Correspondence to Bartosz A. Grzybowski.

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The authors hold patents related to material synthesis in rotary devices: South Korea Patent Application 10-2019-0008413 (B.A.G. and Y.I.S.), Patent WO2020/153739 (O.C., B.M.-K., Y.I.S. and B.A.G.).

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Grzybowski, B.A., Sobolev, Y.I., Cybulski, O. et al. Materials, assemblies and reaction systems under rotation. Nat Rev Mater 7, 338–354 (2022). https://doi.org/10.1038/s41578-021-00404-x

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