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From lipids to lipid nanoparticles to mRNA vaccines

Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of lipid nanoparticle–nucleic acid drugs.

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Correspondence to Christine Horejs.

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Horejs, C. From lipids to lipid nanoparticles to mRNA vaccines. Nat Rev Mater 6, 1075–1076 (2021).

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