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Lung cancer

Chemotherapy in EGFR-mutated NSCLC: optimizing combinations with TKIs and amivantamab

Recent results from the FLAURA2 and MARIPOSA-2 trials underline the continued role of chemotherapy in the treatment of patients with EGFR-mutated non-small-cell lung cancer in the era of targeted therapies. Herein, we argue that the most appropriate and rational sequence and/or combination of therapies remains a matter of discussion.

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Correspondence to Rafael Rosell.

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Rosell, R., González-Cao, M. Chemotherapy in EGFR-mutated NSCLC: optimizing combinations with TKIs and amivantamab. Nat Rev Clin Oncol 21, 169–170 (2024). https://doi.org/10.1038/s41571-023-00843-1

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