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Neuroendocrine neoplasia goes molecular — time for a change

In a cohort of 100 patients with neuroendocrine cancer, the use of NETest enabled earlier prediction of tumour progression and resulted in a reduction in the frequency of follow-up procedures. These outcomes are exciting and promising, but limited in value by the heterogeneity of the study cohort and by suboptimal assay sensitivity and specificity.

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The work of G.R. is supported in part by internal university grants (Università Cattolica line D.1/2016-R412500403 and D.1 2017-R412500591).

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Correspondence to Guido Rindi.

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G.R. has received honoraria from Ipsen and Novartis for his role in their speaker’s bureau. B.W. declares no competing interests.

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Rindi, G., Wiedenmann, B. Neuroendocrine neoplasia goes molecular — time for a change. Nat Rev Clin Oncol 16, 149–150 (2019).

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