A highly chemoselective method for the insertion of carbohydrates into existing oligosaccharides has been developed. The reaction sequence involves a selective Lewis-acid catalysed cleavage of one glycosidic bond followed by sequential construction of two new glycosidic bonds.
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Kim, S., O’Doherty, G.A. Tailor-made glycans. Nat Rev Chem (2024). https://doi.org/10.1038/s41570-024-00598-y
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DOI: https://doi.org/10.1038/s41570-024-00598-y