Left atrial appendage occlusion (LAAO) has been rapidly adopted for stroke prevention in patients with non-valvular atrial fibrillation and a contraindication to oral anticoagulation. Ongoing and planned clinical trials on LAAO and the development of new devices might expand clinical indications and address the remaining challenges of device-related thrombus and peridevice leak.
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Acknowledgements
J.S. has received unrestricted research grant support from the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, National Institutes of Health and University of British Columbia Division of Cardiology.
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J.S. has received unrestricted research grant support from Abbott, AstraZeneca, Boston Scientific, St. Jude Medical and Servier; has received salary support from the Michael Smith Foundation of Health Research; has received speaker honoraria from Abbott, AstraZeneca, Boston Scientific and Sunovion; has received consultancy and advisory board honoraria from Abbott, AstraZeneca, Baylis, Boston Scientific, FEops, Gore and St. Jude Medical; and has received proctorship honoraria from Abbott, Boston Scientific and St. Jude Medical.
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Saw, J. Left atrial appendage occlusion. Nat Rev Cardiol 21, 153–154 (2024). https://doi.org/10.1038/s41569-023-00973-0
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DOI: https://doi.org/10.1038/s41569-023-00973-0
