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Anticoagulation in patients with atrial high-rate episodes

Nature Reviews Cardiology volume 21, pages 5–6 (2024)Cite this article

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The risk of stroke in patients with atrial high-rate episodes (AHREs) depends on age, comorbidities and AHRE burden. Two randomized clinical trials on the use of oral anticoagulant therapy for stroke prevention in older patients with short and rare AHREs have reported conflicting findings on the efficacy of oral anticoagulation in this patient population, although both trials report a significantly increased risk of major bleeding with oral anticoagulation.

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Fig. 1: Randomized clinical trials on oral anticoagulation for stroke prevention in patients with AHREs.

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Authors and Affiliations

  1. Faculty of Medicine, Belgrade University, Belgrade, Serbia

    Tatjana Potpara

  2. Cardiology Clinic, University Clinical Centre of Serbia, Belgrade, Serbia

    Tatjana Potpara

  3. Department of Cardiology, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

    Carina Blomstrom-Lundqvist

  4. Department of Medical Science, Uppsala University, Uppsala, Sweden

    Carina Blomstrom-Lundqvist

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  1. Tatjana Potpara
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  2. Carina Blomstrom-Lundqvist
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Correspondence to Tatjana Potpara.

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The authors declare no competing interests.

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Potpara, T., Blomstrom-Lundqvist, C. Anticoagulation in patients with atrial high-rate episodes. Nat Rev Cardiol 21, 5–6 (2024). https://doi.org/10.1038/s41569-023-00963-2

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