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Improving clinical practice guidelines with implementation science

Clinical practice guidelines provide evidence-informed recommendations to improve the delivery of high-quality health care. Despite their ubiquity, the translation of clinical guidelines into routine clinical practice remains suboptimal. We propose the use of implementation science methods in the development of clinical practice guidelines to improve uptake.

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Fig. 1: Embedding implementation science into the guideline development and translation processes.

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Acknowledgements

M.N.S. is the recipient of a National Health and Medical Research Council Investigator Grant (Emerging Leader Fellowship) commencing in 2022. L.K.J. and S.S.G. receive funding from the National Heart, Lung, and Blood Institute of the NIH. G.F.W. is a recipient of research grants from the National Health and Medical Research Council and Medical Research Future Funds.

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Correspondence to Mitchell N. Sarkies.

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M.N.S. has received personal fees from Amgen. S.S.G. is a consultant to Esperion for the development of clinical trials for new lipid-lowering agents for children. G.F.W. is a consultant to and recipient of research grants from Amgen, Arrowhead, Regeneron and Sanofi; and a consultant to AstraZeneca, Esperion and Pfizer. L.K.J. declares no competing interests.

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Sarkies, M.N., Jones, L.K., Gidding, S.S. et al. Improving clinical practice guidelines with implementation science. Nat Rev Cardiol 19, 3–4 (2022). https://doi.org/10.1038/s41569-021-00645-x

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