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A call for training programmes in cardiovascular genomics

Genomic data are increasingly being integrated into health care. We propose an outline for structured training in cardiovascular genomics, recognizing the growing need for a cardiovascular genomics subspecialty and cardiovascular subspecialists who incorporate genomics advances to optimize the management of heritable cardiovascular diseases.

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Fig. 1: Components of a proposed curriculum for a 1-year fellowship in cardiovascular genomics.


  1. 1.

    Ahmad, F. et al. Establishment of specialized clinical cardiovascular genetics programs: recognizing the need and meeting standards: a scientific statement from the American Heart Association. Circ. Genom. Precis. Med. 12, e000054 (2019).

    Article  Google Scholar 

  2. 2.

    Hazin, R. et al. Ethical, legal, and social implications of incorporating genomic information into electronic health records. Genet. Med. 15, 810–816 (2013).

    Article  Google Scholar 

  3. 3.

    Giudicessi, J. R., Kullo, I. J. & Ackerman, M. J. Precision cardiovascular medicine: state of genetic testing. Mayo Clin. Proc. 92, 642–662 (2017).

    Article  Google Scholar 

  4. 4.

    Dikilitas, O. et al. Predictive utility of polygenic risk scores for coronary heart disease in three major racial and ethnic groups. Am. J. Hum. Genet. 106, 707–716 (2020).

    CAS  Article  Google Scholar 

  5. 5.

    Kullo, I. J. et al. Incorporating a genetic risk score into coronary heart disease risk estimates: effect on low-density lipoprotein cholesterol levels (the MI-GENES clinical trial). Circulation 133, 1181–1188 (2016).

    Article  Google Scholar 

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M.S.S. acknowledges the Cardiovascular Medicine fellowship programme at the University of Kansas Medical Center for fostering a research environment for fellows in training. M.J.A. is supported in part by the Mayo Clinic Windland Smith Rice Comprehensive Sudden Cardiac Death Program. I.J.K. is funded by a National Heart, Lung, and Blood Institute training and mentorship grant (K24-HL70710) and by a National Human Genome Research Institute grant (HG006379).

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Correspondence to Maya S. Safarova.

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The authors declare no competing interests.

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Safarova, M.S., Ackerman, M.J. & Kullo, I.J. A call for training programmes in cardiovascular genomics. Nat Rev Cardiol 18, 539–540 (2021).

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