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Drug dosing for heart failure: does sex or size matter?

Results from a prospective study by Santema and colleagues suggest that women with heart failure and reduced ejection fraction might need lower doses of standard heart failure drugs than men. However, this conclusion was formed on the basis of data from a small proportion of the population studied and might only be relevant to participants taking β-blockers.

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Fig. 1: Relationship between recommended HF drug dose and risk of death or hospitalization for HF3.


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Correspondence to Andrew J. S. Coats.

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Coats, A.J.S. Drug dosing for heart failure: does sex or size matter?. Nat Rev Cardiol 16, 705–706 (2019).

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