Imaging through a strongly diffusive medium remains an outstanding challenge, in particular in applications in biological and medical imaging. Here, we propose a method based on a single-photon time-of-flight camera that allows, in combination with computational processing of the spatial and full temporal photon distribution data, imaging of an object embedded inside a strongly diffusive medium over more than 80 transport mean free paths. The technique is contactless and requires 1 s acquisition times, thus allowing Hz frame rate imaging. The imaging depth corresponds to several centimetres of human tissue and allows us to perform deep-body imaging as a proof of principle.
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All data used in this work are available from https://doi.org/10.5525/gla.researchdata.642
All codes used in this work are available from https://doi.org/10.5525/gla.researchdata.642
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D.F. acknowledges financial support the Engineering and Physical Sciences Research Council, UK (grants EP/M006514/1 and EP/M01326X/1). Y.W. acknowledges financial support from the Engineering and Physical Sciences Research Council, UK (grants EP/M008843/1 and EP/M011089/1).
The authors declare no competing interests.
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Lyons, A., Tonolini, F., Boccolini, A. et al. Computational time-of-flight diffuse optical tomography. Nat. Photonics 13, 575–579 (2019). https://doi.org/10.1038/s41566-019-0439-x
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