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Escherichia coli integrates chemotaxis and quorum sensing pathways in vivo

Chemotaxis towards the interspecies quorum sensing signal autoinducer 2 (AI-2) promotes gut colonization by Escherichia coli and is linked to fructoselysine metabolism. The differential ability of E. coli strains to chemotactically respond to AI-2 further leads to niche segregation and co-existence of E. coli strains in the murine gut.

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Fig. 1: Wild-type and non-chemotactic E. coli in the gut lumen.

References

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This is a summary of: Laganenka, L. et al. Chemotaxis and autoinducer-2 signalling mediate colonization and contribute to co-existence of Escherichia coli strains in the murine gut. Nat. Microbiol. https://doi.org/10.1038/s41564-022-01286-7 (2023).

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Escherichia coli integrates chemotaxis and quorum sensing pathways in vivo. Nat Microbiol 8, 193–194 (2023). https://doi.org/10.1038/s41564-022-01294-7

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