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FUNGAL GENETICS

Telomere transposon takeover in Cryptococcus

Identification and analysis of mutator strains in the human fungal pathogen Cryptococcus neoformans show that natural loss of RNA interference triggers massive accumulation of Cnl1 retroelements at subtelomeric regions.

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Fig. 1: Flow diagram of screening approach and key findings.

References

  1. Lynch, M. et al. Nat. Rev. Genet. 17, 704–714 (2016).

    CAS  Article  Google Scholar 

  2. Matic, I. Mol. Cell. 75, 421–425 (2019).

    CAS  Article  Google Scholar 

  3. Bui, D. T. et al. Genetics 205, 1459–1471 (2017).

    CAS  Article  Google Scholar 

  4. Bourque, G. et al. Genome Biol. 19, 199 (2018).

    CAS  Article  Google Scholar 

  5. Cosby, R. L., Chang, N. C. & Feschotte, C. Genes Dev. 33, 1098–1116 (2019).

    CAS  Article  Google Scholar 

  6. Kibbler, C. C. et al. Oxford Textbook of Medical Mycology (Oxford Univ. Press, 2017).

  7. Priest, S. J. et al. Nat. Microbiol. https://doi.org/10.1038/s41564-022-01183-z (2022).

    Article  PubMed  Google Scholar 

  8. Feretzaki, M. & Heitman, J. PLoS Genet. 9, e1003688 (2013).

    CAS  Article  Google Scholar 

Download references

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Correspondence to Hiten D. Madhani.

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Huang, M.Y., Madhani, H.D. Telomere transposon takeover in Cryptococcus. Nat Microbiol 7, 1108–1109 (2022). https://doi.org/10.1038/s41564-022-01189-7

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  • DOI: https://doi.org/10.1038/s41564-022-01189-7

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