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PARASITE BIOLOGY

Malaria parasite beats the heat

Nature Microbiology volume 6, pages 1105–1107 (2021)Cite this article

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The malaria parasite Plasmodium falciparum survives fever during human infection by using a transcription factor to regulate its heat-shock response.

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Fig. 1: The ApiAP2 transcription factor PfAP2-HS drives activation of essential heat-shock responses in P. falciparum–infected red blood cells.

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Authors and Affiliations

  1. Department of Microbiology & Immunology, Columbia University Irving Medical Center, New York, NY, USA

    Vandana Thathy & David A. Fidock

  2. Division of Infectious Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA

    David A. Fidock

Authors
  1. Vandana Thathy
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  2. David A. Fidock
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Correspondence to David A. Fidock.

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The authors declare no competing interests.

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Thathy, V., Fidock, D.A. Malaria parasite beats the heat. Nat Microbiol 6, 1105–1107 (2021). https://doi.org/10.1038/s41564-021-00953-5

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