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Stressed-out gut bacteria are pterin up gut inflammation

Nature Microbiology volume 5, pages 1316–1318 (2020)Cite this article

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Sub-inhibitory levels of an antibiotic switch on cryptic stress pathways in Escherichia coli that result in the production of immunomodulatory molecules.

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Fig. 1: General mechanisms through which antibiotics shape the immune system.

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Acknowledgements

This work was supported by the National Institutes of Health (grant nos. R01AR074500 and 1F32AI147456).

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Authors and Affiliations

  1. Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA, USA

    Margaret Alexander & Peter J. Turnbaugh

  2. Chan Zuckerberg Biohub, San Francisco, CA, USA

    Peter J. Turnbaugh

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  1. Margaret Alexander
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  2. Peter J. Turnbaugh
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Correspondence to Peter J. Turnbaugh.

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Competing interests

P.J.T. is on the scientific advisory board for Kaleido, Pendulum, Seres and SNIPRbiome. M.A. declares no competing interests.

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Alexander, M., Turnbaugh, P.J. Stressed-out gut bacteria are pterin up gut inflammation. Nat Microbiol 5, 1316–1318 (2020). https://doi.org/10.1038/s41564-020-00804-9

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