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FUNGAL GENETICS

Selenium strikes back at fungi

Nature Microbiology volume 4, pages 726–727 (2019)Cite this article

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Computational analysis of fungal genomes revealed that some early-branching fungi use selenocysteine, the selenium-containing amino acid, that was thought to be missing from proteins in this lineage.

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Fig. 1: Presence and absence of selenoproteins in eukaryotes.

References

  1. Cone, J. E., DelRio, R. M., Davis, J. N. & Stadtman, T. C. Proc. Natl Acad. Sci. USA 73, 2659–2663 (1976).

    Article  CAS  Google Scholar 

  2. Chambers, I. et al. EMBO J. 5, 1221–1227 (1986).

    Article  CAS  Google Scholar 

  3. Zinoni, F., Birkmann, A., Stadtman, T. C. & Bock, A. Proc. Natl Acad. Sci. USA 83, 4650–4654 (1986).

    Article  CAS  Google Scholar 

  4. Berry, M. J. et al. Nature 353, 273–276 (1991).

    Article  CAS  Google Scholar 

  5. Lescure, A., Gautheret, D., Carbon, P. & Krol, A. J. Biol. Chem. 274, 38147–38154 (1999).

    Article  CAS  Google Scholar 

  6. Kryukov, G.V., Kryukov, V. M. & Gladyshev, V. N. J. Biol. Chem. 274, 33888–33897 (1999).

    Article  CAS  Google Scholar 

  7. Castellano, S. et al. EMBO Rep. 2, 697–702 (2001).

    Article  CAS  Google Scholar 

  8. Kryukov, G. V. et al. Science 300, 1439–1443 (2003).

    Article  CAS  Google Scholar 

  9. Mariotti, M., Salinas, G., Gabaldón, T. & Gladyshev, V. N. Nat. Microbiol. https://doi.org/10.1038/s41564-018-0354-9 (2019).

  10. Chapple, C. E. & Guigo, R. PLoS ONE 3, e2968 (2008).

    Article  Google Scholar 

  11. Mariotti, M. et al. PLoS ONE 7, e33066 (2012).

    Article  CAS  Google Scholar 

  12. Gobler, C. J. et al. ISME J. 7, 1333–1343 (2013).

    Article  CAS  Google Scholar 

  13. Castellano, S. et al. Mol. Biol. Evol. 26, 2031–2040 (2009).

    Article  CAS  Google Scholar 

  14. Arnér, E. S. Exp. Cell Res. 316, 1296–1303 (2010).

    Article  Google Scholar 

  15. Sarangi, G. K., Romagne, F. & Castellano, S. Mol. Biol. Evol. 35, 1744–1756 (2018).

    Article  CAS  Google Scholar 

Download references

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  1. UCL Great Ormond Street Institute of Child Health, Genetics and Genomic Medicine Programme, University College London, London, UK

    Sergi Castellano

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  1. Sergi Castellano
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Correspondence to Sergi Castellano.

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Castellano, S. Selenium strikes back at fungi. Nat Microbiol 4, 726–727 (2019). https://doi.org/10.1038/s41564-019-0434-5

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