ARCHAEAL BIOLOGY

CRISPR–Cas impedes archaeal mating

The early identification of repetitive genomic loci in Haloferax species was instrumental in igniting interest in CRISPR–Cas systems. Now, work in this genus has revealed an important role of CRISPR–Cas in reducing an unusual form of inter-species archaeal mating that occurs by cell fusion.

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Fig. 1: Mating in archaea.

References

  1. 1.

    Jackson, S. A. et al. Science 365, eaal5056 (2017).

    Article  Google Scholar 

  2. 2.

    Marraffini, L. A. & Sontheimer, E. J. Science 322, 1843–1845 (2008).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  3. 3.

    Watson, B. N. J., Staals, R. H. J. & Fineran, P. C. mBio 9, e02406-17 (2018).

  4. 4.

    Rosenshine, I., Tchelet, R. & Mevarech, M. Science 245, 1387–1389 (1989).

    CAS  Article  PubMed  Google Scholar 

  5. 5.

    Noar, A. et al. Curr. Biol. 22, 1444–1448 (2012).

    Article  Google Scholar 

  6. 6.

    Shalev, Y. et al. Front. Microbiol. 8, 1253 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  7. 7.

    Turgeman-Grott, I. et al. Nat. Microbiol. https://doi.org/s41564-018-0302-8 (2018).

  8. 8.

    Brodt, A., Lurie-Weinberger, M. N. & Gophna, U. Biol. Direct 6, 65 (2011).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  9. 9.

    Silas, S. et al. eLife 6, e27601 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  10. 10.

    Patterson, A. G. et al. Molec. Cell 64, 1102–1108 (2016).

    CAS  Article  Google Scholar 

Download references

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Correspondence to Peter C. Fineran.

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Fineran, P.C. CRISPR–Cas impedes archaeal mating. Nat Microbiol 4, 2–3 (2019). https://doi.org/10.1038/s41564-018-0326-0

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