It is now clear that key autophagy proteins possess alternative functions, distinct from their conventional roles in autophagy. Adding to this emerging field, a new study shows how ATG16L1 acts to promote plasma membrane repair following damage by pore-forming bacteria.
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Florey, O. The double life of autophagy proteins. Nat Microbiol 3, 1334–1335 (2018). https://doi.org/10.1038/s41564-018-0310-8
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DOI: https://doi.org/10.1038/s41564-018-0310-8
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Trehalose promotes the survival of random-pattern skin flaps by TFEB mediated autophagy enhancement
Cell Death & Disease (2019)