News & Views | Published:

MICROBIOME

Bacterial butyrate prevents atherosclerosis

Nature Microbiologyvolume 3pages13321333 (2018) | Download Citation

Gut microbiota are known to produce an intermediate metabolite in the production of trimethylamine N-oxide that promotes atherosclerosis. Now, another metabolite produced by the same bacteria has been identified that prevents atherosclerosis. The basis for these opposing microbial effects are dictated by diet.

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Change history

  • 03 January 2019

    In the version of this News & Views originally published, owing to production error, the concentration scales given for butyrate circulates in the bloodstream and colon were incorrect. It was stated that “butyrate circulates at mM levels (as opposed to µM in colon)”; this should have read “butyrate circulates at µM levels (as opposed to mM in colon)”. This error has now been corrected.

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Author information

Affiliations

  1. Department of Genetics and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC, USA

    • Scott J. Bultman

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Competing interests

The author declares no competing interests.

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Correspondence to Scott J. Bultman.

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DOI

https://doi.org/10.1038/s41564-018-0299-z

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