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BACTERIAL SECRETION

Tagging the type VI secretion system

Nature Microbiologyvolume 3pages11901191 (2018) | Download Citation

A powerful in vivo biotinylation approach identifies TagA as a binding partner of TssA, a central regulator of the assembly of the type VI secretion system (T6SS). TagA terminates assembly of the T6SS tail and tethers it to the membrane, acting as a crossbow latch that allows for efficient firing.

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Author information

Affiliations

  1. Department of Structural Biology and Chemistry, Biochemistry of Macromolecular Interactions Unit, Institut Pasteur, Paris, France

    • Olivera Francetic
  2. CNRS UMR 3528, Institut Pasteur, Paris, France

    • Olivera Francetic

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The author declares no competing interests.

Corresponding author

Correspondence to Olivera Francetic.

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DOI

https://doi.org/10.1038/s41564-018-0277-5

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